CDB15:0000732 GZMB — CHRM3

Experimentally validated in Human, Mixed species; Orthology-inferred in Human, Mouse, Rat, Frog, Zebrafish, Chicken, Macaque, Pig, Dog, Cow, Chimp, Horse, Marmoset, Sheep

Title

Journal:; Year Published:

Abstract

Novel fragments of the Sjögren's syndrome autoantigens alpha-fodrin and type 3 muscarinic acetylcholine receptor generated during cytotoxic lymphocyte granule-induced cell death.

Arthritis and rheumatism, 2001; PubMed, Homo sapiens GZMB — Homo sapiens CHRM3
ABSTRACT: To determine whether the Sjögren's syndrome autoantigens alpha-fodrin and the type 3 muscarinic acetylcholine receptor (M3R) are cleaved during cytotoxic lymphocyte granule-induced death, to yield novel fragments.
Basic Information on GZMB
Ligand Name: granzyme B
Other Symbols: CTLA1, CSPB, CCPI, CGL-1, CSP-B, CGL1, CTSGL1, HLP, SECT
Ligand Location: secreted based on hpa, perplexity, uniprot
HGNC Gene Symbol Report: GZMB
GeneCards: GZMB
Functional Annotations for GZMB
Gene Ontologies: PAN-GO, AmiGO 2
Expression Profile: Human Protein Atlas (RNA and protein), Human Cell Atlas (RNA), GEPIA cancer vs normal (RNA), GeneCards (RNA and protein)
Disease Annotations: MalaCards, OMIM, Open Targets Platform, DISEASES (text mining), AI summary (LLM)
Interactions with other Receptors for GZMB
GZMB — IGF2R
Basic Information on CHRM3
Receptor Name: cholinergic receptor muscarinic 3
Other Symbols: m3AChR
Receptor Location: cell membrane based on hpa, perplexity, uniprot
HGNC Gene Symbol Report: CHRM3
GeneCards: CHRM3
Functional Annotations for CHRM3
Gene Ontologies: PAN-GO, AmiGO 2
Expression Profile: Human Protein Atlas (RNA and protein), Human Cell Atlas (RNA), GEPIA cancer vs normal (RNA), GeneCards (RNA and protein)
Disease Annotations: MalaCards, OMIM, Open Targets Platform, DISEASES (text mining), AI summary (LLM)
Interactions with other Ligands for CHRM3
SLURP2 — CHRM3
← CDB15 GUCA2B GUCY2D
CDB15 GZMB IGF2R →