CDB15:0000154 C1QTNF5 — MFRP

Experimentally validated in Mouse; Orthology-inferred in Human, Rat, Frog, Zebrafish, Chicken, Macaque, Pig, Dog, Cow, Chimp, Horse, Marmoset, Sheep

Title

Journal:; Year Published:

Abstract

174delG mutation in mouse MFRP causes photoreceptor degeneration and RPE atrophy.

Investigative ophthalmology & visual science, 2011; PubMed, Mus Musculus C1qtnf5 — Mus Musculus Mfrp

ABSTRACT: The authors have identified a recessive mutation causing progressive retinal degeneration, white fundus flecks, and eventual retinal pigment epithelium (RPE) atrophy. The goal of these studies was to characterize the retinal phenotype, to identify the causative locus, and to examine possible functions of the affected gene.

Basic Information on C1QTNF5

Ligand Name: C1q and TNF related 5

Other Symbols: CTRP5, DKFZp586B0621, LORD

Ligand Location: secreted based on perplexity, uniprot, cell membrane based on perplexity

HGNC Gene Symbol Report: C1QTNF5

GeneCards: C1QTNF5

HGNC Gene Group: C1q domain containing

Functional Annotations for C1QTNF5

Gene Ontologies: PAN-GO, AmiGO 2

Expression Profile: Human Protein Atlas (RNA and protein), Human Cell Atlas (RNA), GEPIA cancer vs normal (RNA), GeneCards (RNA and protein)

Disease Annotations: MalaCards, OMIM, Open Targets Platform, DISEASES (text mining), AI summary (LLM)

Interactions with other Receptors for C1QTNF5

C1QTNF5 — ADIPOR1

Basic Information on MFRP

Receptor Name: membrane frizzled-related protein

Other Symbols: FLJ30570, rd6, NNO2, C1QTNF5

Receptor Location: cell membrane based on perplexity, uniprot

HGNC Gene Symbol Report: MFRP

GeneCards: MFRP

HGNC Gene Group: unknown

Functional Annotations for MFRP

Gene Ontologies: PAN-GO, AmiGO 2

Expression Profile: Human Protein Atlas (RNA and protein), Human Cell Atlas (RNA), GEPIA cancer vs normal (RNA), GeneCards (RNA and protein)

Disease Annotations: MalaCards, OMIM, Open Targets Platform, DISEASES (text mining), AI summary (LLM)

Interactions with other Ligands for MFRP

PTN — MFRP