CDB15:0001510 TNFSF4 — TNFRSF4

Experimentally validated in Rat; Orthology-inferred in Human, Mouse, Chicken, Macaque, Pig, Dog, Cow, Chimp, Horse, Marmoset, Sheep

Title

Journal:; Year Published:

Abstract

Association of the CD134/CD134L costimulatory pathway with acute rejection of small bowel allograft.

Transplantation, 2002; PubMed, Rattus norvegicus Tnfsf4 — Rattus norvegicus Tnfrsf4

ABSTRACT: The CD134/CD134L interaction provides a strong costimulatory signal that is CD28-independent. The CD134/CD134L pathway has been studied in inflammatory, autoimmune diseases, and graft-versus-host disease, but no information exists on the involvement of CD134/CD134L interactions in solid organ transplantation.

Basic Information on TNFSF4

Ligand Name: TNF superfamily member 4

Other Symbols: TXGP1, OX-40L, gp34, CD252

Ligand Location: cell membrane based on perplexity

HGNC Gene Symbol Report: TNFSF4

GeneCards: TNFSF4

HGNC Gene Group: CD molecules, Receptor ligands: Tumor necrosis factor superfamily

Functional Annotations for TNFSF4

Gene Ontologies: PAN-GO, AmiGO 2

Expression Profile: Human Protein Atlas (RNA and protein), Human Cell Atlas (RNA), GEPIA cancer vs normal (RNA), GeneCards (RNA and protein)

Disease Annotations: MalaCards, OMIM, Open Targets Platform, DISEASES (text mining), AI summary (LLM)

Interactions with other Receptors for TNFSF4

Basic Information on TNFRSF4

Receptor Name: TNF receptor superfamily member 4

Other Symbols: TXGP1L, ACT35, OX40, CD134

Receptor Location: cell membrane based on perplexity

HGNC Gene Symbol Report: TNFRSF4

GeneCards: TNFRSF4

HGNC Gene Group: CD molecules, Tumor necrosis factor receptor superfamily

Functional Annotations for TNFRSF4

Gene Ontologies: PAN-GO, AmiGO 2

Expression Profile: Human Protein Atlas (RNA and protein), Human Cell Atlas (RNA), GEPIA cancer vs normal (RNA), GeneCards (RNA and protein)

Disease Annotations: MalaCards, OMIM, Open Targets Platform, DISEASES (text mining), AI summary (LLM)

Interactions with other Ligands for TNFRSF4