CDB25:0003955 MMP2 — PECAM1

Experimentally validated in Rat; Orthology-inferred in Human, Mouse, Frog, Zebrafish, Chicken, Macaque, Pig, Dog, Cow, Chimp, Horse, Marmoset, Sheep

Title

Journal:; Year Published:

Abstract

Loss of Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1) in the Diabetic Retina: Role of Matrix Metalloproteinases.

Investigative ophthalmology & visual science, 2019; PubMed, Rattus norvegicus Mmp2 — Rattus norvegicus Pecam1
ABSTRACT: To test the hypothesis that high glucose and matrix metalloproteinases (MMPs) contribute to the diabetes-induced loss of platelet endothelial cell adhesion molecule-1 (PECAM-1) in the retinal microvasculature.
Basic Information on MMP2
Ligand Name: matrix metallopeptidase 2
Other Symbols: CLG4, CLG4A, TBE-1
Ligand Location: secreted based on hpa, perplexity, uniprot
HGNC Gene Symbol Report: MMP2
GeneCards: MMP2
HGNC Gene Group: Metallopeptidases
Functional Annotations for MMP2
Gene Ontologies: PAN-GO, AmiGO 2
Expression Profile: Human Protein Atlas (RNA and protein), Human Cell Atlas (RNA), GEPIA cancer vs normal (RNA), GeneCards (RNA and protein)
Disease Annotations: MalaCards, OMIM, Open Targets Platform, DISEASES (text mining), AI summary (LLM)
Interactions with other Receptors for MMP2
MMP2 — FGFR1
Basic Information on PECAM1
Receptor Name: platelet and endothelial cell adhesion molecule 1
Other Symbols: CD31
Receptor Location: cell membrane based on hpa, perplexity, uniprot
HGNC Gene Symbol Report: PECAM1
GeneCards: PECAM1
Functional Annotations for PECAM1
Gene Ontologies: PAN-GO, AmiGO 2
Expression Profile: Human Protein Atlas (RNA and protein), Human Cell Atlas (RNA), GEPIA cancer vs normal (RNA), GeneCards (RNA and protein)
Disease Annotations: MalaCards, OMIM, Open Targets Platform, DISEASES (text mining), AI summary (LLM)
Interactions with other Ligands for PECAM1
CD177 — PECAM1 ・ CD38 — PECAM1 ・ LGALS3 — PECAM1 ・ PECAM1 — PECAM1
← CDB25 MMP2 FGFR1
CDB25 MMP9 IFNAR1 →