CDB15:0000464 EDN3 — EDNRA

Experimentally validated in Human; Orthology-inferred in Mouse, Rat, Frog, Zebrafish, Chicken, Macaque, Pig, Dog, Cow, Chimp, Horse, Marmoset, Sheep

Title

Journal:; Year Published:

Abstract

Endothelin-3 induces both human and opossum gallbladder contraction mediated mainly by endothelin-B receptor subtype in vitro.

Journal of gastroenterology and hepatology, 2002; PubMed, Homo sapiens EDN3 — Homo sapiens EDNRA
ABSTRACT: Endothelins are produced by gallbladder epithelial cells, suggesting a role in the regulation of gallbladder function.
Basic Information on EDN3
Ligand Name: endothelin 3
Other Symbols: ET3
Ligand Location: secreted based on perplexity, uniprot
HGNC Gene Symbol Report: EDN3
GeneCards: EDN3
Functional Annotations for EDN3
Gene Ontologies: PAN-GO, AmiGO 2
Expression Profile: Human Protein Atlas (RNA and protein), Human Cell Atlas (RNA), GEPIA cancer vs normal (RNA), GeneCards (RNA and protein)
Disease Annotations: MalaCards, OMIM, Open Targets Platform, DISEASES (text mining), AI summary (LLM)
Interactions with other Receptors for EDN3
EDN3 — EDNRB
Basic Information on EDNRA
Receptor Name: endothelin receptor type A
Other Symbols: ET-A, ETA-R, hET-AR
Receptor Location: cell membrane based on hpa, perplexity, uniprot
HGNC Gene Symbol Report: EDNRA
GeneCards: EDNRA
HGNC Gene Group: 7TM proteins
Functional Annotations for EDNRA
Gene Ontologies: PAN-GO, AmiGO 2
Expression Profile: Human Protein Atlas (RNA and protein), Human Cell Atlas (RNA), GEPIA cancer vs normal (RNA), GeneCards (RNA and protein)
Disease Annotations: MalaCards, OMIM, Open Targets Platform, DISEASES (text mining), AI summary (LLM)
Interactions with other Ligands for EDNRA
EDN1 — EDNRA ・ EDN2 — EDNRA
← CDB15 EDN2 EDNRB
CDB15 EDN3 EDNRB →