CDB25:0003182 BPI — GPC4

Experimentally validated in Cow; Orthology-inferred in Human, Mouse, Rat, Frog, Zebrafish, Chicken, Macaque, Pig, Dog, Chimp, Horse, Marmoset, Sheep

Title

Journal:; Year Published:

Abstract

Glypican 4, a membrane binding protein for bactericidal/permeability-increasing protein signaling pathways in retinal pigment epithelial cells.

Investigative ophthalmology & visual science, 2007; PubMed, Bos taurus BPI — Bos taurus GPC4

ABSTRACT: Originally identified as a lipopolysaccharide binding protein with Gram-negative bactericidal activity in the leukocytes, bactericidal/permeability-increasing protein (BPI) has been shown to induce various effects in retinal cells in vivo and in vitro.

Basic Information on BPI

Ligand Name: bactericidal permeability increasing protein

Other Symbols: BPIFD1

Ligand Location: secreted based on perplexity, uniprot, cell membrane based on perplexity

HGNC Gene Symbol Report: BPI

GeneCards: BPI

HGNC Gene Group: BPI fold containing

Functional Annotations for BPI

Gene Ontologies: PAN-GO, AmiGO 2

Expression Profile: Human Protein Atlas (RNA and protein), Human Cell Atlas (RNA), GEPIA cancer vs normal (RNA), GeneCards (RNA and protein)

Disease Annotations: MalaCards, OMIM, Open Targets Platform, DISEASES (text mining), AI summary (LLM)

Interactions with other Receptors for BPI

Basic Information on GPC4

Receptor Name: glypican 4

Other Symbols: K-glypican

Receptor Location: cell membrane based on hpa, perplexity, uniprot

HGNC Gene Symbol Report: GPC4

GeneCards: GPC4

HGNC Gene Group: Proteoglycans

Functional Annotations for GPC4

Gene Ontologies: PAN-GO, AmiGO 2

Expression Profile: Human Protein Atlas (RNA and protein), Human Cell Atlas (RNA), GEPIA cancer vs normal (RNA), GeneCards (RNA and protein)

Disease Annotations: MalaCards, OMIM, Open Targets Platform, DISEASES (text mining), AI summary (LLM)

Interactions with other Ligands for GPC4

COL18A1 — GPC4 ・ FGF2 — GPC4 ・ LRRTM4 — GPC4